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PUMA, a novel proapoptotic gene, is induced by p53 - PubMed
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The majority of PUMA induced apoptosis occurs through activation of the tumor suppressor protein p53. p53 is activated by survival signals such as glucose deprivation and increases expression levels of PUMA. This increase in PUMA levels induces apoptosis through mitochondrial dysfunction. p53, and with it PUMA, is activated due to DNA damage caused by a variety of genotoxic agents. Other agents that induce p53 dependent apoptosis are neurotoxins, proteasome inhibitors, micro… WebFeb 12, 2024 · Example: Puma Future Z 2.3. Puma Third Tier: 3.X. The “3.” cleats show a true drop in the hierarchy, similar compared to Nike or Adidas. Puma’s third-level cleats … WebThis is the ULTRA – PUMA’s all new lightweight, speed-focused soccer cleat. Today I have the full family of PUMA ULTRA cleats with me, to run you through the... structural post anchors