Webb13 feb. 2024 · Relapsed epithelial ovarian cancer (EOC) is frequently treated with pegylated liposomal doxorubicin (PLD). Unfortunately, most patients do not benefit from treatment. Prediction of response is crucial to optimize PLD use and avoid unnecessary toxicities. We aimed at assessing the value of topoisomerase II alpha (TOP2A) expression as … Webb16 aug. 2024 · Pegylated liposomal doxorubicin (PLD) is a nano-doxorubicin anticancer agent. It was used as early as 2014 to treat ovarian and breast cancer, multiple myeloma …
Efficacy of PD-1/PD-L1 inhibitors in ovarian cancer: a single-arm meta
WebbUltimately, adding durvalumab to PLD yielded a tolerable safety profile and showed promising efficacy in patients with platinum-resistant recurrent ovarian cancer. “The study met its primary endpoint with improvement in PFS6. We confirm the negative impact of LRP1B deletions on PLD-based therapies,” Dr O'Cearbhaill and colleagues concluded. Webb9 mars 2024 · The 2024 NCCN Guidelines included PLD as a first-line chemotherapy regimen for ovarian cancer, and a regimen of carbo combined with PLD is recommended … tesni odnosi
Efficacy of PD-1/PD-L1 inhibitors in ovarian cancer: a single-arm …
WebbEligible patients (aged ≥18 years) had histologically confirmed epithelial ovarian, primary peritoneal, or fallopian tube carcinoma with first disease recurrence more than 6 months … Webb7 aug. 2012 · This study was previously presented at the 2011 American Society of Clinical Oncology Annual Meeting: Marth C, Alexandre J, Hanker LC, et al. Pegylated liposomal doxorubicin and carboplatin (C-PLD) versus paclitaxel and carboplatin (C-P) in platinum-sensitive ovarian cancer (OC) patients (pts): Treatment at recurrence and overall survival … Webb4 apr. 2024 · Caelyx pegylated liposomal is a medicine used to treat the following types of cancer in adults: metastatic breast cancer in patients at risk of heart problems. ‘Metastatic’ means the cancer has spread to other parts of the body. Caelyx pegylated liposomal is used on its own for this disease; advanced ovarian cancer in women whose previous ... batman gta 5 ped