Pisosterol

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August undefined, 2024

WebSep 12, 2024 · Possible Side Effects. The current evidence suggests that phytosterol supplements are relatively safe and well-tolerated. 5 Side effects, if any, tend to be mild and may include constipation, nausea, … WebA fluorescence in situ hybridization study in an HL60 cell line, using a locus-specific probe for C-MYC, before and after treatment with pisosterol suggests that cells that do not show a high degree of C- MYC gene amplification have a less aggressive and invasive behaviour and are easy targets for chemotherapy. The leukaemia cell line HL60 is widely used in …

Inhibitory effect of pisosterol on human glioblastoma cell ... - DeepDyve

WebFeb 3, 2024 · It is confirmed that the ATM/ATR signaling pathway is a critical mechanism for G2/M arrest in pisosterol-induced glioma cell cycle arrest and suggest that this compound might be a promising anticancer candidate for further investigation. BACKGROUND Pisosterol, a triterpene derived from Pisolithus tinctorius, exhibits potential antitumor … robert clergerie bloss sandals white

Pisosterol Induces G2/M Cell Cycle Arrest and Apoptosis via the …

WebBeta-pisosterol C33H54O4 CID 139586069 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... WebTools. β-sitosterol, a prototypical phytosterol. Phytosterols are phytosteroids, similar to cholesterol, that serve as structural components of biological membranes of plants. [1] … WebJan 13, 2010 · After treatment, no effects were detected at lower concentrations of pisosterol (0.5 and 1.0 μg/mL). However, at 1.8 μg/mL only 15% of the cells presented … robert clergerie caliente sandals

Antitumor activity of pisosterol in mice bearing with S180 tumor

WebHowever, at 1.8 µg ml⁻¹ of pisosterol, only 33% of U343 cells and 15% of AHOL1 cells presented more than two fluorescent signals, suggesting that pisosterol blocks the cells with gene amplification. Cells that do not show a high degree of C-MYC gene amplification have a less aggressive and invasive behavior and are easy targets for ... WebDownload scientific diagram Molecular structure of pisosterol isolated from Pisolithus tinctorius from publication: Cell cycle arrest induced by Pisosterol in HL60 cells with gene amplification ... robert clerg us pressWebBeta-pisosterol C33H54O4 CID 139586069 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … robert clergerie clogs

"WebAug 1, 2011 · Despite the remarkable progress in the characterization of the molecular pathogenesis of glioblastoma multiforme (GBM), these tumors remain incurable and, in most cases, refractory to aggressive cytotoxic treatments. We conducted a morphological and cytogenetic study in two GBM cell lines (U343 and AHOL1), before and after treatment … " - Pisosterol

Pisosterol

WebPisosterol, a triterpene derived from Pisolithus tinctorius, exhibits potential antitumor activity in various malignancies. However, the molecular mechanisms that mediate the pisosterol-specific ... WebWe conducted a study in U343 and AHOL1 glioblastoma cell lines, before and after treatment with the triterpene pisosterol. Using fluorescence in situ hybridization analysis …

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WebBackground: Pisosterol, a triterpene derived from Pisolithus tinctorius, exhibits potential antitumor activity in various malignancies. However, the molecular … WebAug 1, 2007 · The antiproliferative effect of pisosterol was determined by inhibition of DNA synthesis based on BrdU incorporation into HL-60 proliferating cells. It appears that pisosterol-treated cells, despite displaying a differentiated phenotype, continued to proliferate at all doses tested after 72 h, with a slightly decrease at 5 μg/mL. Apoptosis …

WebMay 9, 2008 · Pisosterol is a triterpene isolated from the fungus Pisolithus tinctorius that has been shown to possess a wide variety of biological properties. WebAntitumor activity of pisosterol (50 or 100 mg/m2) was confirmed in mice bearing Sarcoma 180 tumor cells. The tumor growth inhibition ratios were 43.0% and 38.7% for mice treated with pisosterol at 50 and 100 mg/m2, respectively. Histopathological analysis of liver, kidney and spleen was also evaluated.

WebPisosterol, a triterpene derived from Pisolithus tinctorius, exhibits potential antitumor activity in various malignancies. However, the molecular mechanisms that mediate the... WebJun 1, 2008 · We further performed a pulse test, in which the cells treated with pisosterol (0.5, 1.0, and 1.8 microg/ml) were washed and re-incubated in the absence of pisosterol.

WebBackground: Pisosterol, a triterpene derived from Pisolithus tinctorius, exhibits potential antitumor activity in various malignancies. However, the molecular mechanisms that mediate the pisosterol-specific effects on glioma cells remain unknown. Objective: This study aimed to evaluate the antitumoral effects of pisosterol on glioma cell lines.

WebNov 9, 2010 · We conducted a study in U343 and AHOL1 glioblastoma cell lines, before and after treatment with the triterpene pisosterol. Using fluorescence in situ hybridization analysis we showed that 72% of U343... robert clergerie casting velour bootsWebNov 9, 2010 · After treatment, no effects were detected at lower concentrations of pisosterol (0.5 and 1.0 µg ml −1 ). However, at 1.8 µg ml −1 of pisosterol, only 33% of U343 cells … robert clergerie discountWebAug 1, 2011 · Pisosterol lacked activity on mouse erythrocytes as well as on the development of sea urchin eggs, but strongly inhibited the growth of all seven tumor cell lines tested, especially the leukemia ... robert clergerie comWebMar 1, 2010 · Pisosterol lacked activity on mouse erythrocytes as well as on the development of sea urchin eggs, but strongly inhibited the growth of all seven tumor cell lines tested, especially the leukemia ... robert clergerie online shopWebJul 1, 2004 · Pisosterol lacked activity on mouse erythrocytes as well as on the development of sea urchin eggs, but strongly inhibited the growth of all seven tumor cell lines tested, especially the leukemia ... robert clergerie leather slidesWebLoop is the open research network that increases the discoverability and impact of researchers and their work. Loop enables you to stay up-to-date with the latest discoveries and news, connect with researchers and form new collaborations. robert clergerie elastic driver pumpsWebpisosterol. Molecular Formula C 33 H 54 O 4; Average mass 514.779 Da; Monoisotopic mass 514.402222 Da; ChemSpider ID 10182670 robert clergerie online