A Logan plot (or Logan graphical analysis) is a graphical analysis technique based on the compartment model that uses linear regression to analyze pharmacokinetics of tracers involving reversible uptake. It is mainly used for the evaluation of nuclear medicine imaging data after the … Zobacz więcej The kinetics of radiolabeled compounds in a compartmental system can be described in terms of a set of first-order, constant-coefficient, ordinary differential equations. The time course of the activity in the multicompartmental … Zobacz więcej • Patlak plot • Multi-compartment model • Positron emission tomography • Binding potential Zobacz więcej http://doc35.pmod.com/pxmod/pmclass.lib.pmod.models.PMloganV2.htm
Unsupervised PET logan parametric image estimation using …
WitrynaA graphical method of analysis applicable to ligands that bind reversibly to receptors or enzymes requiring the simultaneous measurement of plasma and tissue radioactivities for multiple times after the injection of a radiolabeled tracer is presented. WitrynaLogan's graphical model is a robust estimation of the total distribution volume (DVt) of reversibly bound radiopharmaceuticals, but the resulting DVt values decrease with increasing noise. patricia a bridewell
Logan Plot - PMOD
Witryna10 lut 2024 · LGA is a time-efficient and a computationally efficient algorithm applicable to reversibly binding receptors [ 2, 3 ]. It transforms data of PET tissue time-activity curves (tTACs) into a simple linear relationship, and BPND can then be estimated from the slope of this relationship using the ordinary least-squares (OLS) method. WitrynaAbstract. Logan graphical analysis (LGA) is a method for in vivo quanti cation of tracer kinetics in positron emission tomography (PET). The Witryna2 lut 2024 · The Logan plot is a widely used algorithm for the quantitative analysis of neuroreceptors using PET because it is easy to use and simple to implement. The … patricia a brill